Exploring Socioeconomic Disparities in Health using Microbial Pathways: Insights from Metagenomics

The gut microbiome, known to influence inflammation and mental health, has recently been found to be significantly shaped by social and environmental factors. My PhD research aims to address a critical gap in the literature regarding how socioeconomic position (SEP) impacts the gut microbiome and its implications for health outcomes, particularly inflammation and mental health. I aim to utilize a multi-omics approach, incorporating metagenomics, metatranscriptomics, and metabolomics, with the Lifelines DEEP cohort, alongside a metagenomics-based analysis using the Lifelines DAG3 cohort. My research will explore these relationships across different life stages, with a focus on identifying key overlapping microbial pathways