''LIFE-PPD: detection of alpha-synuclein in serum in the prodromal phase of Parkinson's disease'' A collaboratoin with the Lifelines biobank

Parkinson's disease is caused by misfolding of proteins. With a new method, called seeding amplification assay, these proteins have been detected in the blood of persons with Parkinson's disease (PD). In this study, we will investigate whether we can detect these proteins in the blood in the years before the diagnosis. This can help us with the early detection of the disease but will also tell us more about the biologic processes of the disease. If we are able to diagnose PD before people get symptoms, we may be able to prevent this disease in the future