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Sex differences in the role of early and adult life stress exposure on ADHD persistence and comorbid health conditions in adulthood

We will investigate sex differences in the role of adverse childhood events (ACEs) and adult life stress exposure on adult ADHD symptoms and diagnosis and to what extent this association is modified by genetic risk for ADHD among females and males in the general population. Additionally, we will examine potential sex differences in the associations between early and adult life stress exposure and psychiatric and somatic conditions in adults with and without ADHD and potential modification by ADHD genetic risk.

Year of approval

2025

Institute

UMCG - Interdisciplinary Center Psychopathology & Emotion regulation (ICPE)

Primary applicant

Hartman, C.